Interview with Paul W. Ewald at: http://www.emergingworlds.com/pro_interviews_detail.cfm?Content=120
Paul
W. Ewald, professor of biology at
Amherst College, was the first recipient of the George R. Burch Fellowship in
Theoretic Medicine and Affiliated Sciences.
The publication of his "Evolution of Infectious Disease"
is widely acknowledged by doctors and scientists as a watershed in the
emergence of the new discipline of evolutionary medicine. He has been featured in The Atlantic,
Newsweek, Discover, and Forbes.
Professor
Paul Ewald is the author of a new, ground-breaking book, "Plague Time; How Stealth
Infections Cause Cancers, Heart Disease and other Deadly Ailments." Ewald has been acclaimed for years as one of
the most important thinkers alive today on the genesis of disease and
evolutionary biology. He lives
in Amherst, Massachusetts.
Education:
B.Sc. (1975) University of California, Irvine; Biological Sciences.
Ph.D. (1980) University of Washington; Zoology; specialization in Ecology and
Evolution.
Research: Evolution of infectious diseases.
"Most
species of organisms on our planet live in or on other organisms, yet we are
just beginning to understand one of the most basic questions about this kind of
life style: What determines the point to which such associations evolve along
the spectrum from mutualism to extreme virulence. Because viruses and bacteria
can evolve extremely rapidly, evolutionary experiments can be conducted during
a matter of months in a laboratory setting. Research in my lab makes use of
this rapid evolution by studying experimentally the evolution of virulence.
Using a nuclear polyhedrosis virus that infects gypsy moths, we are
investigating how timing of transmission and genetic heterogeneity within hosts
alters evolution of virulence. My research on disease also takes a comparative
approach to the evolution of virulence, with a focus on human diseases and the
evolutionary effects of various public health interventions. " Prof. Paul Ewald
Selected
Publications:
Ewald, Paul W. 1996. Guarding against the most dangerous emerging pathogens:
Insights from evolutionary biology. Emerging Infectious Diseases 2:245-257.
Ewald,
P. W. 1995. The evolution of virulence: a unifying link between ecology and
parasitology. Journal of Parasitology 81:659-669.
Ewald,
P. W. 1996. Vaccines as evolutionary tools: The virulence-antigen strategy. In,
CONCEPTS IN VACCINE DEVELOPMENT, (S. H. E. Kaufmann, ed.), Walter de Gruyter
& Co:Berlin, pages 1-25.
Ewald,
P. W. 1994. EVOLUTION OF INFECTIOUS DISEASE. Oxford University Press, New York.
Phone: (413) 542-2168
E-mail: pwewald@amherst.edu